Conducting in vitro fertilization (IVF) in hospitals in Shanghai is the most effective way to prepare expectant parents who have difficulty conceiving for a successful pregnancy. However, IVF not only faces economic pressure, but also cannot achieve the effect of successful IVF pregnancy at the current medical level. That is to say, IVF preparation has a certain success rate, which is probably the concern of most expectant parents about IVF preparation.

Although IVF preparation may fail, the failure rate of IVF preparation is lower compared to other methods. Failure in IVF preparation is not scary. The scary thing is that we didn't face it in the right way. If the cause of the transplant failure is not investigated after the transplant failure, even if the transplant is attempted again, most cases still end in failure. Therefore, after the failure of in vitro transplantation, it is necessary to actively cooperate with the doctor to check the reasons for the transplantation failure, clarify the reasons for the transplantation failure, and take appropriate measures to effectively improve the success rate of the next transplantation.

What is the reason for transplant failure?

Endometrial factors are the most common cause of embryo transfer failure, as many expectant mothers have endometritis and polyps. These two diseases are not present in the daily life of expectant mothers, and even under vaginal ultrasound examination, it is not possible to evaluate whether expectant mothers have endometritis. That is to say, after the expectant mother's transplant fails, our reproductive attending doctor will investigate the cause. If the cause of transplant failure cannot be found on the existing basis, the reproductive attending doctor will request the expectant mother to undergo hysteroscopy to further clarify the cause of transplant failure. If the transplantation fails due to endometritis or endometrial polyps, anti-inflammatory treatment followed by transplantation will greatly increase the implantation rate of the test tube.

2. Under the premise of ensuring the normal chromosomes of the embryo, the quality of the embryo directly determines the success of the transfer. Under the same conditions, the higher the success rate of embryo test tubes, the embryo grade is determined by the quality of eggs and sperm. It is very important to regulate the quality of eggs and sperm of prospective parents before entering the week. Therefore, prospective parents should actively cooperate with the fertility doctor for conditioning, so as to transplant all high-quality eggs and sperm.

3. Coagulation function antiphospholipid antibody syndrome. Abnormal coagulation factors can easily lead to local microthrombosis, insufficient blood supply to the endometrium, and are not conducive to embryo implantation, which is also the reason for repeated transplant failures in expectant mothers. Especially for expectant mothers who have repeatedly failed transplants, it is necessary to check their coagulation function and eliminate the cause of coagulation function.

4. Immune factors: Both spouses have infertility due to immune factors, resulting in repeated failure of in vitro transplantation. For expectant mothers, it is necessary to check for immune factors.

5. After successful in vitro transfer of embryonic chromosome factors, the embryo may experience early fetal arrest or miscarriage, and examination of the aborted fetal villi can clarify the cause. If the chromosomes of the expectant parents are normal and the chromosomes of the embryo are abnormal, it is mainly due to the influence of the elderly on the chromosome abnormalities of the embryo. That is to say, when you find yourself infertile, it is best to prepare the test tube as soon as possible. The younger the expectant mother, the more successful the test tube preparation will be!

If one of the expectant parents has chromosomal abnormalities that lead to embryonic chromosomal abnormalities, the third generation IVF can be performed in Shanghai, and normal embryos can be screened through genetic testing for transplantation, which can greatly improve the success rate of transplantation. Transplant failure is not scary, don't hesitate to ask because you are afraid of being scolded. It is important to cooperate with the reproductive attending physician to investigate the reasons for transplant failure, greatly improving the success of the next transplant.