After in vitro transplantation, the first ultrasound examination may show fetal heart rate and fetal buds, and there is also a possibility of fetal arrest when the second ultrasound examination is performed, because prenatal examination can only see the development of the fetus at that time, and cannot determine whether the fetus will continue to grow and develop healthily in the future. Moreover, there are many factors that can cause the fetus to stop developing during pregnancy. So even with the presence of fetal heart and embryo buds after in vitro transplantation, there is still a possibility of fetal arrest.

The Six Major Factors Causing Abortion

1. Endocrine disorders

The transfer and development of embryos depend on the coordination of complex endocrine systems, and any abnormal connection can lead to miscarriage. In the early stages of development, the fetus requires three hormones: estrogen, progesterone, and chorionic gonadotropin. As a mother, due to insufficient endogenous hormones, it is unable to meet the needs of the embryo, which may lead to embryo birth or miscarriage.

2. Uterine abnormalities

The environment and environment of the embryo in the uterus can affect the embryo. 10% to 15% of miscarriages are caused by uterine defects. Congenital malformations mainly include single angle, double type, septal type, double angle type, etc., causing uterine stenosis and limited blood supply. Abnormal development of intrauterine arteries can cause dyssynchrony of the decidua and abnormal implantation.

3. Three chromosomes

If the chromosome is abnormal, it can also cause embryonic underdevelopment and premature birth. A balanced chromosomal translocation of one spouse can easily cause chromosomal abnormalities in the embryo, leading to embryo miscarriage. The reason for fetal chromosomal abnormalities is that the chromosomes of couples are prone to loss or duplication during the mixing process, leading to chromosomal abnormalities in the fertilized egg and inability to develop normally, which can lead to miscarriage, stillbirth, and fetal malformations. Therefore, couples with chromosomal translocations need to undergo prenatal diagnosis in mid pregnancy to avoid the occurrence of fetal chromosomal diseases.

4. Immune factors

Immune embryo miscarriage is relatively rare and cannot be clearly diagnosed at present. According to the immune theory, a mother's pregnancy is considered an allogeneic transplant because the fetus is a combination of parental genetic material and cannot be identical to the mother. The immune incompatibility between the mother and the fetus resulted in the mother rejecting the fetus.

5. Genital tract infection

In addition to the above factors, early pregnancy miscarriage caused by infection has also received increasing attention from scholars both domestically and internationally. In the early stages of pregnancy, severe TORCH infection can lead to embryo death or miscarriage, while mild infections can also cause embryo malformations. The results show that cytomegalovirus can cause miscarriage, fetal death, etc. Infected, pathogenic bacteria can infect the placenta through the bloodstream, causing damage to the placental chorion and capillary endothelium, disrupting the placental barrier, leading to fetal miscarriage, cessation of embryonic development, and fetal malformations.

6. Environmental factors

The changes in physiological conditions during pregnancy greatly alter the mother's absorption, distribution, and excretion of therapeutic drugs and various environmental harmful substances. Early embryos are highly sensitive to the effects of therapeutic drugs and environmental factors. At this point, various harmful factors can cause embryo damage or even loss. Early embryonic death and fetal malformation are also important reasons due to medication and environmental factors. Environmental hormones directly act on the central nervous endocrine regulatory system, causing reproductive hormone secretion disorders, decreased fertility, and abnormal embryonic development.

So during the process of IVF, everyone must pay attention to protecting themselves, resting more, and supplementing with sufficient nutrition. At the same time, attention should be paid to avoiding the above six points to prevent fetal arrest. 592 Baby Net editor wishes everyone a successful test tube test.