Does endometrial hyperplasia affect the success rate of in vitro fertilization?

2023-08-19 本站作者 【 字体:

The success rate of in vitro fertilization (IVF) in women with endometrial hyperplasia is very low, and excessive thickness or thickness of the endometrium can lead to pregnancy failure. So what is endometrial hyperplasia? Let's take a look together with the editor.

Endometrial hyperplasia is a non physiological endometrial glandular hyperplasia lesion, which can be said to be a common gynecological tumor and a precancerous lesion of endometrial cancer. The older the age, the higher the probability of endometrial hyperplasia, with 133 out of 100000 people suffering from it every year. Women aged 50 to 54 are at high risk and are rare among women under 30 years old.

Does endometrial hyperplasia affect the success rate of in vitro fertilization?(图1)

Clinical manifestations of endometrial hyperplasia.

1. Symptoms: Premenopausal women have abnormal uterine bleeding (such as menstrual pattern, frequency, length, and amount of bleeding) and bleeding during menstruation. In a systematic review of premenopausal women, the risk of bleeding during menstruation is higher than in patients with increased menstrual volume. Vaginal bleeding in postmenopausal women is the main symptom of endometrial cancer, and any postmenopausal vaginal bleeding requires further examination.

2. Physical signs: There may be no abnormalities during the physical examination, but only an increase in body mass index (BMI) and polycystic ovary syndrome. Uterine double diagnosis should be performed regularly, and if necessary, cytological examination and endometrial biopsy should be improved. Postmenopausal bleeding is recommended for routine endometrial sampling.

Methods for diagnosing and monitoring endometrial hyperplasia.

The diagnosis of endometrial hyperplasia and endometrial cancer depends on endometrial biopsy. Diagnostic hysteroscopy is more helpful in obtaining specimens than conventional endometrial biopsy. Especially when ordinary endometrial biopsy specimens are highly suspected of endometrial hyperplasia or endometrial cancer, persistent vaginal bleeding, and failure to obtain specimens, their advantages are even more prominent.

Does endometrial hyperplasia affect the success rate of in vitro fertilization?(图2)

Patients with endometrial hyperplasia must be treated before undergoing in vitro fertilization, and then consider undergoing in vitro fertilization. Due to the thickness or thickness of the endometrium, pregnancy failure can occur. Generally speaking, the impact of an excessively thin endometrium is more pronounced, as once the endometrium is too thin, even if the embryo is directly transplanted into the uterus, it may not be implanted or may easily fall off after implantation, leading to miscarriage. Therefore, experts suggest that patients must adjust the thickness of the endometrium before undergoing in vitro fertilization. After adjusting the thickness of the endometrium, it generally meets the requirements of in vitro fertilization.

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