The rapid development of modern society has also made most people fall behind. So, what are the manifestations of non obstructive azoospermia? Can it be treated? Non obstructive azoospermia is mainly characterized by unclear male characteristics, such as laryngeal nodules, whiskers, etc., all caused by insufficient secretion. In addition, non obstructive azoospermia can also lead to a decrease in male sexual desire, such as being less susceptible to sexual stimulation or avoiding sexual activity. The most direct manifestation is male infertility, where men cannot produce sperm or combine with eggs to form fertilized eggs.

Most non obstructive azoospermia is caused by testicular dysfunction. This situation may be congenital developmental abnormalities, acquired injuries, torsion, or prostatitis. Therefore, when men experience non obstructive azoospermia, active treatment measures should be taken to avoid delaying the optimal treatment time. What are the clinical manifestations of non obstructive azoospermia?

1、 The male characteristics are not obvious.

This symptom mainly refers to the lack of obvious features such as beard in male laryngeal nodules, as most non obstructive azoospermia is caused by testicular torsion and injury. In this case, testicular torsion and injury can lead to a decrease in androgen secretion. In addition, azoospermia can also affect male androgens. Therefore, men can treat fatigue by supplementing with androgens to reduce the lack of obvious male characteristics.

2、 Decreased libido.

Its manifestation is that men are unwilling to have sexual relations with women, unable to meet their sexual needs, leading to women's wild thoughts and one-sided belief that there is a rift in the relationship between the two parties. Even non obstructive azoospermia patients find it difficult to achieve orgasm during sexual activity, which can affect the quality of sexual life for both men and women, and in severe cases, may lead to a deterioration of marital relationships. Therefore, for male patients with azoospermia, active cooperation with treatment should be taken to control further deterioration of the condition.

3、 Infertility

Due to the inability of non obstructive azoospermia patients to produce sperm normally, it will result in sperm not being able to bind to the eggs produced by women, thus preventing the achievement of fertility goals. This is usually due to congenital reasons such as azoospermia, testicular development, abnormal position, etc., which are difficult to cure. If it is temporary azoospermia caused by acquired testicular injury or prostatitis, it can be treated by surgical repair or the use of relevant antibiotics to eliminate inflammation, thus achieving the goal of treating azoospermia.

How to treat non obstructive azoospermia?

If there is no obstructive azoospermia, endocrine therapy is usually required. Drug therapy can enable 10% to 15% of non obstructive azoospermia patients to discover sperm in the semen and use its assisted reproductive technology to achieve fertility. If sperm does not appear during endocrine therapy, it is usually recommended to undergo surgical treatment, namely testicular microspermy (micro TESE). Some testes may have some curved seminiferous tubules that can produce sperm normally, which is what we call local spermatogenesis. Use a high-definition microscope to examine the testes, identify these local spermatogenic tissues from the testes, and then separate them using a high-resolution microscope.