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Is it possible for fetal arrest to transplant 4bb and 4aa blastocysts? What is the probability?

2023-08-19 本站作者 【 字体:

Is it possible for fetal arrest to transplant 4bb and 4aa blastocysts? What is the probability? I am 31 years old this year. After getting married, I got pregnant once and had a curettage surgery at 8 weeks, but I haven't been pregnant again. So I have a test tube. Because the quality of the eggs and sperm I extracted was relatively good, we treated the blastocysts according to the doctor's advice and cultured two blastocysts, one was 4bb blastocyst and the other was 4aa blastocyst. Is it possible for these blastocysts to miscarry?

Is it possible for fetal arrest to transplant 4bb and 4aa blastocysts? What is the probability?(图1)

4bb and 4aa blastocysts belong to high-quality embryos, and the probability of fetal abortion after transplantation is very low. But if there are chromosomal abnormalities in the blastocyst, there may be fetal arrest after transplantation. In addition, there are many factors that can cause fetal arrest, not only the embryo itself, but also factors such as the woman's age, uterine environment, living environment, and maternal immunity. So, if the patient's health is not good and the uterine environment is not good, even if 4bb and 4aa blastocysts are transplanted, fetal arrest may occur. It is recommended that patients go to the hospital for a comprehensive examination before extracorporeal transplantation to regulate their body and avoid the possibility of fetal arrest after transplantation.

Most abortions occur between 10 and 12 weeks of pregnancy. The most obvious feeling for a pregnant mother is that the symptoms of pregnancy will gradually disappear, such as the feeling of vomiting during pregnancy, and there are many reasons for fetal arrest. If the following situations occur, fetal arrest may occur after 4bb and 4aa blastocyst transplantation:

Embryonic chromosomal abnormalities

Although the quality of 4bb and 4aa blastocysts is relatively good, there may also be chromosomal abnormalities caused by factors such as parental inheritance or meiosis of fertilized eggs. For embryos with chromosomal abnormalities, it is difficult to survive and therefore prone to fetal arrest.

Reproductive endocrine factors

The implantation and sustained development of transplanted 4bb and 4aa blastocysts depend on the coordination of the complex endocrine system of the mother. Early pregnancy is mainly characterized by estrogen, progesterone, and human chorionic gonadotropin. If the mother's own hormone levels are insufficient to meet the needs of embryonic development, it may lead to embryo termination and miscarriage.

maternal factors

The fetus is born to the mother. When pregnant women suffer from systemic diseases or are infected with a certain virus, it may lead to abnormal embryonic development or early miscarriage. In addition, if a woman has reproductive diseases such as uterine malformations, uterine fibroids, or uterine adhesions, both the uterine environment and the overall uterine environment may have an impact on the embryo, leading to fetal arrest.

environmental factor

Pregnant women themselves may be affected by ionizing radiation, or they may use some prohibited drugs during pregnancy, which may lead to embryonic malformations, threatened miscarriage, or even termination of in vitro fertilization. It is recommended that patients pay attention to strengthening nursing during pregnancy, and try not to blindly use drugs or come into contact with radioactive substances.

Immune factors

In recent years, research has found that immune factors are one of the main causes of fetal arrest or spontaneous abortion, especially after two or more abortions. After 4bb and 4aa blastocyst transplantation, there is a high possibility of fetal arrest. Is it possible for fetal arrest to transplant 4bb and 4aa blastocysts? What is the probability?

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