Due to factors such as increased work pressure, severe environmental pollution, and unhealthy lifestyle habits, many modern couples have reached as many as 50 million infertility cases in China. For difficult to conceive populations, the effective solution is to use IVF assisted reproduction. So will maternal anemia affect the success rate of in vitro fertilization in the United States?

The effect of anemia in expectant mothers on the success rate of in vitro fertilization

Anemia refers to the situation where the red blood cell count, hemoglobin content, and red blood cell backlog are below normal standards in a certain volume of circulating blood. Irregular daily routines and nutritional disorders can also lead to anemia. In clinical practice, anemia usually manifests as symptoms such as fatigue, dizziness, irritability, and decreased attention.

Test tube experts say that anemia in women generally does not affect the smooth progress and success rate of the test tube cycle. If mild anemia does not affect IVF after examination, then the cycle can be carried out directly. But if female anemia symptoms are severe, it can have adverse effects on the fetus after pregnancy. It should be noted that fetal growth and development in the uterus require sufficient oxygen and nutrition to ensure normal growth and development. For expectant mothers with severe anemia symptoms, their blood oxygen carrying capacity becomes very low, which can easily lead to placental hypoxia, leading to degeneration and infarction of placental villi, causing asphyxia in the uterine cavity of the fetus, leading to fetal arrest and miscarriage, seriously endangering the safety and health of the mother and baby. Therefore, experts suggest that women with anemia should first check and determine the type and degree of anemia before entering the IVF cycle in the United States. Then, targeted diagnosis and treatment and scientific adjustment should be carried out. After the symptoms of anemia improve and the body recovers, IVF can be performed to ensure a more secure success rate.

How to avoid the impact of anemia on test tubes

1. Scientific recuperation

Anemic women can eat more green vegetables and foods with high iron content during pregnancy preparation and pregnancy, such as spinach, kelp, lean meat, black sesame, brown sugar, cherries, longans, etc. They can also consume foods rich in vitamin C to help better absorb iron; In daily life, it is important to quit smoking and alcohol, avoid staying up late, and ensure sufficient sleep; Learn to reduce stress appropriately, relax, and maintain a positive and optimistic attitude; Maintaining appropriate aerobic exercise every day, such as jogging and yoga, not only enhances physical fitness and immunity, but also helps improve egg quality, laying a favorable foundation for in vitro fertilization.

2. Conduct IVF cycle

After obtaining healthy blastocysts and entering the in vitro cycle, in vitro experts will develop a dedicated ovulation promotion plan based on the woman's age, ovarian function, and basal follicle count, using natural, side effect free drugs certified by the US FDA for ovulation promotion. And during the medication period, the development of follicles is monitored through B-ultrasound throughout the entire process, and the dosage and duration of drugs are adjusted in a timely manner based on women's response to drugs, ensuring women's safety and health while achieving good ovulation promoting effects. When the follicles mature (1-2≥ 18mm, 2-3≥ 17mm), injection of a puncture needle (HCG or Lupron) will be arranged, and the eggs will be retrieved after 36 hours. The entire egg retrieval process is guided by ultrasound and can be completed in about 10 minutes, without causing any pain to women.

Then high-quality eggs and sperm are fertilized in the laboratory, and the fertilized eggs are cultivated until the 5th day to form a blastocyst. Then, experts use PGS/PGD gene screening diagnostic technology to detect the number and structure of all chromosomes in the blastocyst, check for abnormalities, and diagnose gene mutation points to avoid the impact of 274 genetic diseases on the fetus, ensuring the health of the blastocyst from the root cause.

3. Appropriate timing for transplantation to improve implantation rate

Before blastocyst transplantation, test tube experts will conduct ultrasound examinations on the female uterus to check whether the endometrium meets the standards and whether its morphology and structure are normal. If the thickness of the endometrium does not meet the standard or if there are diseases or abnormalities in the uterus, experts will first diagnose and treat it to meet the pregnancy requirements. That is, when the thickness of the endometrium is moderate (8-12mm), blood flow is rich, cell separation is good, and the uterine cavity shape is normal, qualitative and quantitative transplantation will be carried out according to the customer's reproductive needs. After transplantation, experts will combine the actual situation of pregnant mothers and inject an appropriate amount of natural progesterone/HCG to promote the proliferation of corpus luteum cells and the synthesis and secretion of progesterone, support corpus luteum function, improve uterine receptivity, and facilitate better implantation, growth, and development of blastocysts. At the same time, it is recommended that expectant mothers regularly test their blood values and prenatal tests throughout the entire pregnancy period to ensure the smooth progress of the entire cycle.