With the relaxation of the second child policy, some reproductive centers have seen a significant increase in the number of elderly couples consulting with IVF at the beginning of their consultations. Some are already preparing to conceive, and the "second child wave" has quietly arrived. But doctors say that once a woman reaches the age of 45, the success rate of IVF is very low, at less than 5%.

The success rate of IVF at the age of 45

Although there are many successful cases of in vitro fertilization at the age of 45 in clinical practice, it is not recommended for elderly mothers to "gamble their lives" to give birth again. Previously, it was the elderly mothers who lost their wives and then lost their soldiers when doing in vitro fertilization. Now, with the relaxation of the second child policy, more and more elderly couples want to do in vitro fertilization.

You should know that 'in vitro fertilization' is not the 100% success rate we imagine. According to reports, generally speaking, the success rate of women over 45 years old is very low, with a success rate of less than 5%. This is because the quality and quantity of eggs in women will decrease with age, and even if pregnancy is successful, the miscarriage rate and embryo malformation rate will also increase. Therefore, it is necessary to conduct a comprehensive evaluation of the suitability of giving birth at an advanced age.

People over 45 years old have a success rate of less than 5%

Nowadays, due to the combined effects of advanced age and various factors, it is more difficult for infertile patients to seek medical treatment in hospitals.

There is a set of data: "For women under the age of 30, the success rate of IVF will reach over 60%; between the ages of 30-35, the success rate of IVF will be over 50%; between the ages of 35-40, the success rate will be less than 40%; and between the ages of 40-45, the average success rate will be only about 20%.

The effect of age on the success rate of in vitro fertilization

1、 Ovarian aging in elderly women

For women over the age of 35, the quality of their eggs has decreased. Even if the sperm quality is good, the quality of the combined fertilized eggs and embryos will not be high, which can lead to many fertility risks and affect the success rate of in vitro fertilization.

2、 Aging of the uterus in elderly women

For elderly women over the age of 35, the uterus is also incomparable compared to young women. We know that the uterus is the organ for women to give birth to babies, and the uterine environment directly affects embryo implantation and growth and development. If the uterus undergoes pathological changes, it can lead to IVF failure.

3、 Older women experience a decrease in hormone levels in their bodies

The hormone levels in the human body can affect many organs, such as the endometrium of women. If the hormone levels in women decrease, the endometrium will become thinner or thicker, which is not conducive to embryo implantation. This affects the success rate of in vitro fertilization.

In summary, female patients over 45 years old are not suitable for in vitro fertilization. The most important reason is that "these women have poor ovarian function, high rates of egg abnormalities, high rates of embryo abnormalities, high miscarriage rates, high rates of birth defects, and very low birth rates. Therefore, it is recommended that elderly women with poor egg quality should undergo early treatment before considering IVF until the egg quality is feasible, in order to ensure the success rate of IVF.