According to relevant data, the number of infertility cases in China has exceeded 50 million, and about 35% of the difficult to conceive population is caused by male factors. There are many conditions that can lead to male infertility, such as weak sperm, oligospermia, azoospermia, immune factors, and so on.

What are the causes of male asthenozoospermia?

In vitro fertilization experts in the United States say that normal men's A-level sperm are generally≥ 25% or a+b level≥ 50% (A level indicates good sperm motility, moving forward in a straight line; B level indicates average sperm motility, only moving forward in a curved line; C level indicates poor sperm motility, only wriggling in place). If the above standards are not met, it indicates low sperm motility, also known as asthenozoospermia, which can reduce fertilization rate and subsequently lead to infertility.

Causes of asthenozoospermia:

1. Reproductive infection: Men suffer from inflammation of the reproductive tract or reproductive glands, such as seminal vesiculitis, prostatitis, orchitis, etc. These can affect sperm motility and reduce their ability to penetrate egg cells, causing partial sperm membrane defects or structural damage, and even having a direct toxic effect on sperm, thereby reducing sperm motility.

2. Endocrine abnormalities: Endocrine hormones in normal individuals are the main source of sperm nutrition, and sperm production and development rely on endocrine hormones to provide nutrition. When endocrine hormones are insufficient, it can seriously affect sperm growth and development.

Immune factors: Typically, anti sperm antibodies can hinder sperm motility, reduce quality, and result in a large number of abnormal sperm.

3. Abnormal semen liquefaction: High semen viscosity is one of the causes of asthenospermia. When semen does not liquefy, slender fibrin appears in the seminal plasma and forms a network with each other, reducing the space for sperm movement and thus limiting sperm forward movement.

4. Varicocele: Patients with varicocele can experience problems such as blood retention, microcirculatory disorders, nutrient deficiency, or decreased oxygen partial pressure, which can affect sperm production and subsequently lead to decreased sperm motility.

5. Poor dietary habits, such as long-term smoking, drinking alcohol, or a preference for food, can lead to a decrease in sperm motility, as alcohol and nicotine in cigarettes can directly and indirectly damage sperm; In addition, long-term exposure to ionizing radiation or chemicals can cause a decrease in sperm motility or malformation.

A typical male ejaculation requires about 100 to 200 million sperm. For in vitro fertilization, there is a high probability that American in vitro experts will select dozens of healthy, complete, and energetic sperm from them.

How to improve success rate

1. Semen washing treatment - Select high-quality sperm from male semen, of which 5% are sperm and 95% are seminal plasma. Some components of seminal plasma (such as anti sperm antibodies, dead sperm, pathogenic microorganisms, etc.) can affect fertilization or increase the rate of abnormal embryo formation. So American experts will first use density gradient centrifugation to select high-quality sperm. This technology uses advanced Perecoll sperm washing solution, avoiding the drawbacks of previous washing solutions that can kill sperm. At the same time, it can effectively adjust semen concentration and sperm motility to help improve fertilization rate.

2. ICSI Single Sperm Injection - After optimizing the fertilization rate of eggs, American experts will use single sperm follicular plasma injection ICSI technology, which directly injects selected high-quality single sperm into the egg cell with microscopic assistance to combine the two, ensuring the utilization rate of each egg and increasing the probability of forming a fertilized egg.

3. PGS/PGD gene screening and testing - To achieve healthy and eugenics, American experts will cultivate fertilized eggs into blastocysts composed of over 100 cells on the fifth day, which have stable morphological structure and higher implantation ability; Then, PGS/PGD technology is used to conduct gene screening and diagnosis on the blastocyst. By comprehensively screening the number and structure of 23 pairs of chromosomes in the blastocyst, it is determined whether there are chromosomal abnormalities, and gene mutation points are diagnosed whether there are genes carrying genetic defects, effectively avoiding the impact of more than 200 genetic diseases on the fetus in the future.

American in vitro fertilization experts suggest that before going to the United States for a week, men also need to work with women to improve their lifestyle habits, such as quitting smoking and drinking; Reduce work pressure, avoid staying up late and maintain sufficient sleep; In terms of diet, it is important to eat foods containing high-quality protein, including beef and mutton, eggs, and any foods rich in arginine, as arginine is a necessary component for sperm production; Adhere to at least aerobic exercise, such as swimming, running, etc., to enhance physical fitness; Avoid behaviors that affect sperm quality such as soaking in hot springs, taking saunas, staying away from ionizing radiation, and wearing tight pants.